Find Rhonda Patrick at:Foundmyfitness.com, @foundmyfitness, Mixed Martial Arts (MMA) and Brain Injury, Rhonda recently had her first exposure of MMA with Joe at UFC, Multiple blow effect lead to a damaging chain reaction, Key Chemicals/Supplements for Brain Health, (I wonder if @Bonobos knew this when naming their company? Dr. Rhonda Patrick obtained her Ph.D. in biomedical science from the University of Tennessee Health Science Center in Memphis, Tennessee. But duration is pretty accurate. Patrick: So Ive been doing the sauna five or six days per week. Additionally, Dr. Rhonda graduated with a Bachelor of Science degree in biochemistry . JRE #459 - Dr. Rhonda Patrick : r/JoeRogan - Reddit All notes are independently created and do not imply any sponsorship or endorsement by the source podcast. Rhonda Perciavalle Patrick has a Ph.D. in biomedical science from the University of Tennessee Health Science Center, Memphis TN, and St. Jude Children's Research Hospital, Memphis, TN. Your IP: Podcast Notes is a Signal From the Noise LLC Production, All Right Reserved, Berkshire Hathaway Annual Shareholders Meeting, Christopher Lockhead's Follow Your Different, Everyday Espionage Podcast with Andrew Bustamante, Feel Better, Live More With Dr. Rangan Chatterjee, Logocentrifugal Podcast With Chance Lunceford, Moonshots and Mindsets with Peter Diamandis, Network State Podcast with Balaji Srinivasan, Spearhead with Naval Ravikant and Babak Nivi, The Jolly Swagman Podcast with Joseph Walker, The Underworld Podcast with Danny Gold and Sean Williams, The Unraveling Podcast with Jocko Willink and Darryl Cooper, This Week in Startups with Jason Calacanis, Where It Happens with Sahil Bloom and Greg Isenberg, Most people on ketogenic diet are probably not actually achieving ketosis, Ketogenic diet isnt just about extreme low carb you have to be intentional about consuming very high fat, There are differences between fasting state and ketosis but you will make beta hydroxybutyrate and produce a lot of gabba in both cases which can improve cognitive function, Omega-3s are critical in diet: people with low omega-3 index have higher all cause mortality and lower lifespan, The quality of food makes a huge difference in micronutrient profile (and taste), Exercise can be tricky when trying to achieve ketosis: aerobic exercise can stimulate it, strength training can kick you out, Sauna use could offer a great way for the body to mimic exercise in people who are disabled, depressed, or otherwise not willing to exercise. Its associated with so many things. Joe Rogan Experience Podcast Episode #1701 Dr. Rhonda Patrick ( @foundmyfitness ) has a PhD in biomedical science and is an expert on nutritional health, the brain and aging. The first year it hit me hard because I wasnt sleeping because every three hours you have to feed the baby.if(typeof ez_ad_units != 'undefined'){ez_ad_units.push([[250,250],'sleepline_com-large-leaderboard-2','ezslot_6',659,'0','0'])};__ez_fad_position('div-gpt-ad-sleepline_com-large-leaderboard-2-0'); Rogan: Thats a giant factor in your immune system. In that case, you might also like the FoundMyFitness podcast (also available on Spotify ), which features many great interviews with Rhonda's favorite heroes of science, exploring the frontier of human healthspan. In this week's Infinite Loops, join Jim O'Shaughnessy and Ed Latimore as they discuss stoicism, progress, pain, authenticity, and balancing FREE when you join over 50,000 subscribers to the Podcast Notes newsletter. His work has appeared in GQ, Teen Vogue, Man Repeller and MTV. And would have been an interesting contrast in her levels (she's quite active) vs her mom's levels (sedentary). She has dedicated her research career to finding proactive and preventive solutions to aging and longevity. In this this episode of The Matt Walker Podcast, Matt Walker & Craig Canapari continue their two part discussion behind the science of FREE when you join over 50,000 subscribers to the Podcast Notes newsletter. Amyloid beta plaques are one of the key markers of your likelihood of developing Alzheimer's. Sleep: Also helps your body cleanse out amyloid beta plaques. MzI2OGQ4YTBiODIyZWI1NDE1OGJkZjhhZDE3OWI5MmJhZThjN2QzMjQ4MzRh Dr. Rhonda Patrick | Joe Rogan Experience - Podcast Notes Dr. Rhonda Patrick is a biomedical scientist focused on nutrition and health. 77 To help support the investigation, you can pull the corresponding error log from your web server and submit it our support team. All notes are intended to reflect the podcast and have not beenindependentlyverified. YmM5YzhmYTNjYjhmOTQ4YzUyYTAzNGYwODBmNTVhMDZiNDRlZjcwMmIwNWI3 Its a modern-day version of getting ripped off at your local mattress store. Psst the sleep review industry is full of liars, sharks, and thieves. Dr. Patrick has been a guest of Joe Rogan Experience ten times. She has done extensive research on aging . A lot of the genes had to do with learning memory, cognition, and metabolism. Itll tell you: hey, you should get to bed since youve been getting up at 6 oclock in the morning so you should go to bed by 10 tonight. Company About Jobs For the Record Communities Its awful. If you believe Wordfence should be allowing you access to this site, please let them know using the steps below so they can investigate why this is happening. ZDA1MDBmMTcyYmJkZGI0OWQxYWZhOGJkOGQ4N2Q4NjA0MTY0ZTRhYzZkYzcz Its bad for you and its bad for your spouse. I have a history of night terrors. Rogan: Like crazy.if(typeof ez_ad_units != 'undefined'){ez_ad_units.push([[300,600],'sleepline_com-leader-4','ezslot_13',666,'0','0'])};__ez_fad_position('div-gpt-ad-sleepline_com-leader-4-0'); Patrick: But when you wear it you dont snore? Share on Facebook SHARE. NDc0ODM1MDcwYmFmZWUwNTk3ZTcyZjgyZWNmMDliYmMzOGZhZmUwMzFjMDIz I have the Phillips Hue and at 5 oclock all the lights in our house go red. She is also the host of Found My Fitness podcast. New comments cannot be posted and votes cannot be cast. I think that someones in the room and theyre going to come get me and I freak out and I scream. In breast milk, oligosaccharhides are very plentiful, They cant be digested by the inflants digestive system, and are there solely to feed the infants gut microbiome, specifically increasing the species bifidobacterium infantis, The stem cells in breast milk get digested, and go to into the bloodstream, and travel to different organs to further development, After you have the baby, this effect decreases, making a lot of mothers feel sad, Also adding to the postpartum depression, new moms dont get enough light, and sleep is drastically altered. So I just go into crazy mode. Podcast Notes is a Signal From the Noise LLC Production, All Right Reserved, Berkshire Hathaway Annual Shareholders Meeting, Christopher Lockhead's Follow Your Different, Everyday Espionage Podcast with Andrew Bustamante, Feel Better, Live More With Dr. Rangan Chatterjee, Logocentrifugal Podcast With Chance Lunceford, Moonshots and Mindsets with Peter Diamandis, Network State Podcast with Balaji Srinivasan, Spearhead with Naval Ravikant and Babak Nivi, The Jolly Swagman Podcast with Joseph Walker, The Underworld Podcast with Danny Gold and Sean Williams, The Unraveling Podcast with Jocko Willink and Darryl Cooper, This Week in Startups with Jason Calacanis, Where It Happens with Sahil Bloom and Greg Isenberg, Wild Alasakan Salmon Roe from Vital Choice, DHA the omega 3 fatty acid predominantly found in fatty fish, 1% of a fishs DHA is in the phospholipid form, In the roe of a fish (aka fish eggs) 40-70% of the DHA is found in the phospholipid form, Epigenetics changing how much a gene is activated or not activated, In one study, obesity was looked at in fathers. Previous Appearances: #1178, #901 Watch or Listen to JRE #1474 #1473 - Tom Papa Hearst Magazine Media, Inc. All Rights Reserved. Rogan: Snoring is a real issue and its usually because you have an impeded airway. YzJkYmQxYzdmMzk3ZjI0ZmNiNDY5YjI5MWZkNWY2NWYyMjA4ZjQ5MGQxNDkx You know like when youre working out hard sometimes you require more sleep? NTEyOWJmZThjOGY3OGU5ZDEzYjc0OWVjYzQxNzUyNWRlOWVmMzA2ODY4NDM3 List of JRE Rhonda Patrick Episodes : r/JoeRogan - Reddit It shows you really accurate it actually has a sleep coach built in so it shows you how much sleep you got, where your recovery is at, what you need. Download Audio. Do you feel like you need more sleep though? Y2Q4OTkwZWQ1Nzc0ODllNjg2NWM3MzA2OWViMDBmNDg3NjljYWVmMzYxYmEx This is an unofficial transcript meant for reference. Dr. Rhonda Patrick on The Joe Rogan Experience #1474 Dr. Rhonda Patrick | The Joe Rogan Experience Transcripts - Podgist See more resources on Google Dr. Rhonda Patrick on. Rogan: What do you think is not accurate in terms of sleep stages? You get fat and you have all this extra tissue. It happens earlier in my sleep cycle. Patrick: Thats true. OGQyNjM4YzVlM2ZkMWY0ZDE3MjQ4OTA1N2YyN2U5MWMyMmYzNTJkNmYwZWRh Sign up free. Rhonda Patrick Supplements - What Does She Take? - Drug Genius Prior to this, . Generated by Wordfence at Tue, 2 May 2023 4:05:36 GMT.Your computer's time: document.write(new Date().toUTCString());. ZDQzNjZiNTkxODE1NzMxZjdmZjI5YTEwOTEyZjlkZjhlNWMzMWZkNjhhMGVk A protective mechanism against viral, bacterial infections, Be careful of oxidized fish oil (this happens if its too old), Rhonda stopped taking it while breast feeding, she was taking 250 mg/day previously. Cloudflare monitors for these errors and automatically investigates the cause. NzQzOGNmNDgyMjllYjIwNWRmZWYxNTQwYjI4ZjdiMTBkNmNlMWNhZTA2MGU0 Specifically, Rogan will take three teaspoons of Carlson's daily. Podcast Notes is a Signal From the Noise LLC Production, All Right Reserved, Berkshire Hathaway Annual Shareholders Meeting, Christopher Lockhead's Follow Your Different, Everyday Espionage Podcast with Andrew Bustamante, Feel Better, Live More With Dr. Rangan Chatterjee, Logocentrifugal Podcast With Chance Lunceford, Moonshots and Mindsets with Peter Diamandis, Network State Podcast with Balaji Srinivasan, Spearhead with Naval Ravikant and Babak Nivi, The Jolly Swagman Podcast with Joseph Walker, The Underworld Podcast with Danny Gold and Sean Williams, The Unraveling Podcast with Jocko Willink and Darryl Cooper, This Week in Startups with Jason Calacanis, Where It Happens with Sahil Bloom and Greg Isenberg, Sauna: if you have access use the sauna regularly to improve cardiovascular health and immune functions take a hot bath if you dont have access, Theres a big difference between oral vitamin C and Intravenous vitamin C, You can take vitamin C orally but will need a big dose and it still wont have the same effect; IV once per week if you can, Sleep plays a crucial role in immunity, homeostasis, and regulation of body functions, People are actively working on monoclonal antibodies, Improved therapeutic treatments coming, including more repurposing of drugs that will make things less scary, As you get older your immune system declines, There are lifestyle components of immune system you can be proactive about: exercise, sleep, supplements, nutrition, gut-microbiome health, Besides age, the major regulator of immune function seems to be previous virus exposure, not genetics, At any given point you have antibodies against 10 different viruses but youre not always getting sick, 50-80% of US population has had CMV and most people dont ever know they have had it and show no symptoms, CMV impacts immune function differently depending on when you get it, When youre young, it enhances immune response but for older people its deleterious, Interesting tie-in to COVID-19 because we know older people are more prone to severity, Its likely that theres some cross-immunity happening since SARS-COV-2 viruses is part of beta coronaviruses along with SARS-CoV-1 and MRSA, 15-30% of common colds come from coronaviruses so theres a good hypothesis that potentially one or two of common cold virus antibodies could interact with SARS-CoV-2 and neutralize it, Antibody binds to virus and instead of neutralizing it, changes the configuration so the virus can get into the cell better, This activates the immune system and causes pathology, This results in a higher viral load without antibodies to neutralize, Weve seen it happen with coronaviruses, including SARS-CoV-1 and MRSA, The spike region is where antibodies bind and is also the region the virus uses to get into the cell, Currently seeing two major strain mutations in the spike regions one mutation more prominent in Asia, one mutation more predominant in Europe and North America, Brings to light an interesting genetic link to mutations, Theres a theory that the mutation is causing peoples immune system to become more active and lead to severe COVID-19, Monoclonal antibodies: identify specific antibody that binds to spike protein and manufacture them, Problem is this will offer short lived protection since you are not making your own antibodies as you would with a vaccine, Continuous exploration into repurposing drugs and combination drug treatments, Anecdotally, the majority of people on ventilators die partly because ventilators cause more damage to the lungs and can induce more damage, But its hard to say which came first did the ventilator do the damage or was the damage so severe that the patient needed a ventilator, People with Type O blood seem to be less susceptible to contracting COVID-19, People with Type O blood create Type A antibodies which bind to spike region and neutralize antibody so it cant enter the cell, We saw this in SARS-CoV-1 so maybe same for SARS-CoV-2, Another (unproven) theory: Type O blood people have lower levels of blood factor involved in clotting, Hearing more stories that some prisoners are trying to contract SARS-CoV-2 to get out of jail by spitting in a cup and passing to others, First off, its important to distinguish between asymptomatic and pre-symptomatic, Some people do not have symptoms at the time of testing but develop symptoms later so are actually pre-symptomatic, Its possible that viruses have already gone around that environment so antibodies from those viruses are helping in immunity from SARS-CoV-2, Rhonda was also searching to literature to see whether inmates are vaccinated prior to entering but couldnt find that information, Poor sleep has a huge impact on glucose and spikes and also plays a role in maintaining optimal immune functions, Rhonda takes melatonin to help her sleep, 10 mg/day, Regulating circadian rhythm is crucial for sleep, Rhonda makes sure to have bright light exposure in the morning (e.g., opening curtains, walking outside), and changes the lighting in the house in the evening to red lights, 70% of US population has insufficient Vitamin D levels; 28% are deficient, Body can generate naturally when exposed to sun daily, Obese people in US are also more likely to be vitamin D deficient, Genetic polymorphisms: people that have variations in genes that cause them to have less vitamin D, These people are more likely to die from respiratory infection, African Americans in the US are 28x more deficient in vitamin D than Caucasians, A recent study that looked at COVID-19 patients observed an inverse relationship between vitamin D levels and COVID-19 symptoms: the lower the vitamin D levels, the higher the severity of COVID-19, In Indonesia almost all patients that died from COVID-19 were vitamin D deficient, Melanin blocks ability to produce Vitamin D, In the US and Europe, African Americans and black people are more likely to die from COVID-19, Even when adjusting for SES and lifestyle factors, this was still true so something else must be happening, Tolerable upper intake is 4000 IUs per day but its best to get vitamin D blood test to measure levels, There are clinical studies exploring the role of vitamin D but not many in the US, Rhonda wants to see nurses and first responders take vitamin D to see the role in prevention but those studies are not being done, Joe uses the sauna 7 days/week, 180-degrees for 25 min, Rhonda uses the sauna 5 days/week, 180-degrees for 25 min, Heart rate variability improves, blood pressure goes down, cardiovascular health improves, all-cause mortality decreases, Sauna use also improves immune system and makes you more resilient against infection, Brain-derived neurotropic factors (BDNF) increases with exercise and heat stress (sauna), The positive benefits of physical activity on the cardiovascular system were enhanced when sauna was added, Sauna use increases heat shock proteins which prevent muscle atrophy, neurodegenerative genes, and have anti-depressant effects, People who sat in 160-degree sauna for 30 minutes had a 60% increase in heat shock protein compared to baseline, Large Harvard study being done to assess whether hot yoga increases heat shock protein, Heat shock protein have antiviral activity against influenza A, Regular sauna is heating ambient air which in turn raises core body temperature, Infrared saunas are directly heating body without heating the ambient air for example, in a heating tent or blanket, We know more about the effects of dry sauna, For people who dont have access to sauna, a hot bath is a good modality for heat shock protein, Studies being done to assess whether sauna can have anti-depressant effect on depressed patients, Saunas could also provide an avenue for giving sedentary and disabled people the benefits of physical activity without exercising, Ice baths and cold showers can be comparable to cryotherapy but you have to stay in the cold water longer, Cold shock protein hasnt really been measured in humans, instead whats measured is norepinephrine which has been shown to increase, Cold shock protein and hot shock protein have been shown to improve mood as well, The pharmacokinetics of vitamin C are very different in oral vs IV consumption, Oral vitamin C is good for immune function, etc. Any time I do lunges and squats and heavy leg days Im a zombie for two days. Rogan: Its also great for sleep. Dr. Rhonda Patrick Goes In Depth on the Benefits of Vitamin D NWMyNjEwMGMwYmY4NGE0Y2FkNmY4NTJlYzljZDI5YWM5MTQ0ZGU5ZmU2ZWYy ), Prairie Voles are monogamous and have higher level of vasopressin receptors in their brains vs. other species of voles (, They also grow more receptors while mating which makes them more monogamous, But if you remove these receptors they are no longer monogamous, Similar effect seen in non-human primates who are normally monogamous, Mice without this grow up very fearful/stressed, Seems similar to children with tough childhoods, Likely worse in people who already have polymorphisms for serotonin issues genetically vulnerable, Diet is also connected, Vitamin D is important, Omega 3s as sell, They did a currency experiment with bonobos where money = food, First thing they did was start trading the coins for sex with females. YTg0MmRhYzZjZjcwM2MyYmYxYzhjNGI1Y2ZjOSIsInNpZ25hdHVyZSI6IjZl Rogan also made the argument that people who are healthy and don't have comorbidities have suffered thrombosis and myocarditis as a result of the vaccine, but again, Patrick countered this by highlighting the comparatively low level of risk. "No matter which way you look at it, it is worse to be exposed to the virus," she said. #1474 - Dr. Rhonda Patrick - The Joe Rogan Experience | Podcast on Spotify Home Search Your Library Create Playlist Preview of Spotify Sign up to get unlimited songs and podcasts with occasional ads. Just like people have adverse reactions to certain foods, Once study had a group do 24 high intensity interval cycling classes within 8 weeks at the end of the 8 weeks, average VO2 max was improved 12%, Rhonda recalls one study in which people got more benefits (pshycological and health) from walking within nature compared to on a treadmill, A womans VO2 max has been shown to increase after pregnancy, due to carrying around the extra weight, People with one allele of the ApoE4 gene, can have a 10-20x fold increased risk for CTE (Chronic Traumatic Encephalopathy)resulting from TBI (Traumatic Brain Injury), Rhonda has this gene, you can test for it with, Almost everything has sugar in it, if you go into a grocery store and pick up a random item, more likely that not there will be sugar in it, Saturated fat increases large LDL particle number, which isnt that bad, but when eaten in combination with refined sugar, some of these large LDL particles can be converted to small LDL particles, You cant gage someones risk for heart disease just by looking at LDL cholesterol number, you have to look at LDL size too, The PPAR-Alpha Gene and the Ketogenic Diet, So the ketogenic diet may in fact be detrimental to someone who doesnt have this, a high fat diet would lead to more free fatty acids in the blood stream, making someone more insulin insensitive, inflammatory biomarkers would also increase, Rhonda doesnt follow a ketogenic diet due to the fact that she really likes to get a lot prebiotic fiber for the microbiome, its hard to do this on a ketogenic diet, although its doable, We still really dont know how the ketogenic diet effects the microbiome (my gut biome diversity has gone down on a ketogenic diet), Bacteria in the microbiome eat the fermentable fiber we dont digest (from plants, seeds, nuts, legumes), Rhonda has concern that people dont get enough fermentable fiber on a ketogenic diet, Similar to ATP, used as an energetic currency throughout the body, used for etabolism, Improves physical performance, cognitive performance, Kevin Rose also talked about this supplement, in, Rhonda bought the supplement but isnt currently taking it, One study came out showing higher protein consumption from meat was associated with a higher all cause and cancer mortality. Its happened more than once. Her podcasts and other videos can be found at FoundMyFitness.com. All notes are independently created and do not imply any sponsorship or endorsement by the source podcast. #1474 - Dr. Rhonda Patrick Aired on May 14, 2020 * no books mentioned Joe Rogan Experience Podcast Episode #1474 Dr. Rhonda Patrick ( @foundmyfitness) has a PhD in biomedical science and is an expert on nutritional health, the brain and aging.
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